| Identification | Back Directory | [Name]
Benzamide, 3-(cyclopentyloxy)-N-[3-(1-piperidinylcarbonyl)phenyl]- | [CAS]
2648317-95-5 | [Synonyms]
GLP-1R modulator L7-028
Benzamide, 3-(cyclopentyloxy)-N-[3-(1-piperidinylcarbonyl)phenyl]- | [Molecular Formula]
C24H28N2O3 | [MOL File]
2648317-95-5.mol | [Molecular Weight]
392.49 |
| Chemical Properties | Back Directory | [Boiling point ]
529.9±35.0 °C(Predicted) | [density ]
1.218±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Soluble: =10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml | [form ]
Solid | [pka]
12.98±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GLP-1R modulator L7-028 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM). | [References]
[1] Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16(11):2444-2452. DOI:10.1021/acschembio.1c00552 |
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