| Identification | Back Directory | [Name]
1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl]butyl]- | [CAS]
264869-71-8 | [Synonyms]
1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-1(2H)-pyridinyl]butyl]- | [Molecular Formula]
C25H24FN3O2 | [MDL Number]
MFCD13152371 | [MOL File]
264869-71-8.mol | [Molecular Weight]
417.48 |
| Hazard Information | Back Directory | [Uses]
SLV310 is an orally active dopamine D2 receptor antagonist (Ki: 5 nM) and serotonin reuptake receptor inhibitor. SLV310 antagonizes Apomorphine (HY-12723) induced climbing behaviour and 5-HTP (HY-N0122) induced serotonin syndrome like behaviour in mice (ED50: 5.6 and 5.9 mg/kg, p.o.). SLV310 is an antipsychotic compound and can be used for schizophrenia research[1]. | [References]
[1] van Hes R,et al. SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition. Bioorg Med Chem Lett. 2003 Feb 10;13(3):405-8. DOI:10.1016/s0960-894x(02)00996-4 |
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