| Identification | Back Directory | [Name]
VX | [CAS]
2649467-91-2 | [Synonyms]
4-((2R,3S,4S,5R)-3-(3,4-difluoro-2-hydroxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxamido)picolinamide |
| Hazard Information | Back Directory | [Uses]
Suzetrigine phenol is the phenolate form of the sodium channel modulator Suzetrigine (HY-148800). Suzetrigine (VX-548) is an orally active and highly selective inhibitor of NaV1.8[1][2]. | [References]
[1] Scarnati MS, et al. Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook. Alcohol. 2019 Feb;74:83-93. DOI:10.1016/j.alcohol.2018.03.008
[2] Preparation of substituted tetrahydrofuran amides as modulators of sodium channels. World Intellectual Property Organization, WO2021113627 A1 2021-06-10. |
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