| Chemical Properties | Back Directory | [Boiling point ]
709.4±60.0 °C(predicted) | [density ]
1.50±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
13.90±0.46(predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Nipamovir is a nitroimidazole prodrug. Nipamovir shows comparable antiviral activity to SAMT-247 (HY-102077) and NS-1040 in both cellular assays and a human ex vivo model of HIV infection, along with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively[1]. | [References]
[1] Marco Robello, et al. Prodrug Strategy Extends the Use of Anti-HIV Sulfanylbenzamides for Application In Vivo. ACS Pharmacol. Transl. Sci. December 14, 2023. |
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