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2665-57-8

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2665-57-8 Structure

2665-57-8 Structure
IdentificationBack Directory
[Name]

13-Methoxy-14-[(3R)-17-methoxy-17-oxovobasan-3α-yl]ibogamine-18-carboxylic acid methyl ester
[CAS]

2665-57-8
[Synonyms]

Nsc289066
Conodurine
B640928K229
Conodurine B640243K102
13-Methoxy-14-[(3R)-17-methoxy-17-oxovobasan-3α-yl]ibogamine-18-carboxylic acid methyl ester
Ibogamine-18-carboxylic acid, 13-methoxy-14-[(3α)-17-methoxy-17-oxovobasan-3-yl]-, methyl ester
Ibogamine-18-carboxylic acid, 13-methoxy-14-[(3.alpha.)-17-methoxy-17-oxovobasan-3-yl]-, methyl ester
[Molecular Formula]

C43H52N4O5
[MOL File]

2665-57-8.mol
[Molecular Weight]

704.9
Chemical PropertiesBack Directory
[Melting point ]

222-225 °C (decomp)
[density ]

1.30±0.1 g/cm3(Predicted)
[pka]

17.01±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

Conodurine is a monoterpenoid indole alkaloid. Conodurine can inhibit lysosomal acidification. Conodurineis isolated from the natural Tabernaemontana corymbosa[1].
[References]

[1] Zhang Y, Ding X, Yuan YX, Guo LL, Hao XJ. Cytotoxic Monoterpenoid Indole Alkaloids from Tabernaemontana corymbosa as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification. J Nat Prod. 2020 May 22;83(5):1432-1439. DOI:10.1021/acs.jnatprod.9b00856
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