| Identification | Back Directory | [Name]
Cyclo[L-arginylglycyl-L-α-aspartyl-D-tyrosyl-N6-(1-oxo-5-hexyn-1-yl)-L-lysyl] | [CAS]
2665674-77-9 | [Synonyms]
Alkyne-cRGD
Cyclo[L-arginylglycyl-L-α-aspartyl-D-tyrosyl-N6-(1-oxo-5-hexyn-1-yl)-L-lysyl] | [Molecular Formula]
C33H47N9O9 | [MOL File]
2665674-77-9.mol | [Molecular Weight]
713.78 |
| Hazard Information | Back Directory | [Uses]
Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction[1]. | [References]
[1] Zheng J, et al. Bifunctional Compounds as Molecular Degraders for Integrin-Facilitated Targeted Protein Degradation. J Am Chem Soc. 2022 Dec 7;144(48):21831-21836. DOI:10.1021/jacs.2c08367 |
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