| Identification | Back Directory | [Name]
1,3-Dioxolo[4,5-g]isoquinoline-6(5H)-propanol, β,β-difluoro-5-[3-fluoro-5-[[(3S)-1-(3-fluoropropyl)-3-pyrrolidinyl]amino]-2-pyridinyl]-7,8-dihydro-7-methyl-, (5S,7R)- | [CAS]
2667015-33-8 | [Synonyms]
ER degrader 1
1,3-Dioxolo[4,5-g]isoquinoline-6(5H)-propanol, β,β-difluoro-5-[3-fluoro-5-[[(3S)-1-(3-fluoropropyl)-3-pyrrolidinyl]amino]-2-pyridinyl]-7,8-dihydro-7-methyl-, (5S,7R)- | [Molecular Formula]
C26H32F4N4O3 | [MOL File]
2667015-33-8.mol | [Molecular Weight]
524.56 |
| Hazard Information | Back Directory | [Uses]
ER degrader 1 is a potent degrader of estrogen receptor (ER). The estrogen signaling system plays an important role in regulating cell growth, differentiation and apoptosis. ER degrader 1 has the potential for the research of cancer diseases (extracted from patent WO2021139756A1, compound 11)[1]. | [References]
[1] Fanglong Yang, et al. Tricyclic tetrahydroisoquinoline derivatives, their preparation methods and their application in medicine. Patent WO2021139756A1. |
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