| Identification | Back Directory | [Name]
Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- | [CAS]
2667585-44-4 | [Synonyms]
Benzamide, 4-methoxy-N-[(3-oxocyclopentadecyl)methyl]- | [Molecular Formula]
C24H37NO3 | [MOL File]
2667585-44-4.mol | [Molecular Weight]
387.56 |
| Chemical Properties | Back Directory | [Boiling point ]
571.5±25.0 °C(predicted) | [density ]
0.987±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
14.69±0.46(predicted) |
| Hazard Information | Back Directory | [Uses]
ZM-32 is an inhibitor for human antigen R (HuR), that downregulates the expression of VEGF-A and MMP9, and thus inhibits breast cancer tumor angiogenesis. ZM-32 exhibits broad-spectrum anti-proliferative effects in a variety of cancer cell lines, and exhibits antitumor efficacy against MDA-MB-231 in mouse models[1]. | [References]
[1] Yang LQ, et al., Muscone derivative ZM-32 inhibits breast tumor angiogenesis by suppressing HuR-mediated VEGF and MMP9 expression. Biomed Pharmacother. 2021 Apr;136:111265. DOI:10.1016/j.biopha.2021.111265 |
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