| Identification | Back Directory | [Name]
PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN | [CAS]
26685-57-4 | [Synonyms]
SP1
RHSP1
GFRLTNFGYFEPG
H-GFRLTNFGYFEPG-OH
SP3 PROTEIN (HUMAN)
SP1 PROTEIN (HUMAN)
SP1, HUMAN, RECOMBINANT
SCHWANGERSCHAFT PROTEIN-SP1
ANTI-SP1 antibody produced in mouse
PREGNANCY-SPECIFIC BETA 1-GLYCOPROTEIN
GLY-PHE-ARG-LEU-THR-ASN-PHE-GLY-TYR-PHE-GLU-PRO-GLY
PREGNANCY SPECIFIC BETA-1 GLYCOPROTEIN, HUMAN, CORD SERUM
5,5-dimethyl-8-(3-methyloctan-2-yl)-2-(prop-2-yn-1-yl)-2,3,4,5-tetrahydro-1H-chromeno[4,3-c]pyridin-10-ol
8-(1,2-Dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2-(2-propynyl)-2H-[1]benzopyrano[4,3-c]pyridin-10-ol
1,2,3,4-Tetrahydro-2-(2-propynyl)-5,5-dimethyl-8-(1,2-dimethylheptyl)-5H-[1]benzopyrano[4,3-c]pyridine-10-ol
2H-[1]Benzopyrano[4,3-c]pyridin-10-ol, 8-(1,2-dimethylheptyl)-1,3,4,5-tetrahydro-5,5-dimethyl-2-(2-propyn-1-yl)-
1,2,3,4-Tetrahydro-5,5-dimethyl-8-(1,2-dimethylheptyl)-10-hydroxy-2-(2-propynyl)-5H-[1]benzopyrano[4,3-c]pyridine
8-(1,2-DIMETHYLHEPTYL)-1,3,4,5-TETRAHYDRO-5,5-DIMETHYL-2-(2-PROPYNYL)-2H-(1)BENZOPYRANO[4,3-C]PYRIDIN-10-OL(WXG01033) | [Molecular Formula]
C26H37NO2 | [MDL Number]
MFCD01662813 | [MOL File]
26685-57-4.mol | [Molecular Weight]
395.58 |
| Chemical Properties | Back Directory | [Boiling point ]
517.8±50.0 °C(Predicted) | [density ]
1.07±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
buffered aqueous solution | [pka]
9.96±0.40(Predicted) | [biological source]
mouse |
| Hazard Information | Back Directory | [Uses]
Sp1 protein was the first transcription factor to be cloned and characterized. It was first detected in HeLa cells on the basis of its ability to activate the SV40 early promoter transcription. Analysis of structure and function has revealed that Sp1 can be separated into discrete functional domains. The DNA-binding domain consists of three zinc fingers that specifically bind to the GC-box element. | [Biological Activity]
Sp1 protein was shown to recognize and bind selectively to a GC-rich consensus sequence (GC-box: GGGCGG or CACCC) th at presents in the promoter of several important cellular genesincluding Simian vacuolating virus 40 (SV40) earlyhuman immunodeficiency virus-1 (HIV-1)platelet-derived growth factor subunit B (PDGF-B)Mycc-Src etc. In addition to transcriptionSp1 function has been linked to cell growthcancer and Huntington disease. |
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