| Identification | Back Directory | [Name]
3-(dimethoxyphosphinothioylsulfanylmethyl)-5-ethoxy-1,3,4-thiadiazol-2 -one | [CAS]
2669-32-1 | [Synonyms]
NC-2962
GS-12968
LYTHIDATHION
3-(dimethoxyphosphinothioylsulfanylmethyl)-5-ethoxy-1,3,4-thiadiazol-2 -one
Phosphorodithioic acid=S-[(5-ethoxy-2-oxo-1,3,4-thiadiazol-3(2H)-yl)methyl]=O,O-dimethyl ester
Dithiophosphoric acid O,O-dimethyl S-(5-ethoxy-2,3-dihydro-2-oxo-1,3,4-thiadiazol-3-yl)methyl ester | [Molecular Formula]
C7H13N2O4PS3 | [MOL File]
2669-32-1.mol | [Molecular Weight]
316.36 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Lythidathion is an aromatic ether. | [Production Methods]
Commercial production details for lythidathion are not available in open literature. Its structure, however places it squarely within the organothiophosphate insecticides, allowing its industrial synthesis to be inferred from well established organophosphate manufacturing information. Production would centre on constructing the 1,3,4 thiadiazolone heterocycle, typically via condensation of an appropriate hydrazide with a thiocarbonyl or related precursor, followed by O ethylation to install the ethoxy substituent. In parallel, the O,O dimethyl phosphorodithioate fragment would be prepared from phosphorus thiohalide intermediates. The defining step is then S alkylation, in which the thiadiazolone methyl moiety is coupled to the phosphorodithioate under strictly anhydrous, temperature controlled conditions to manage the high reactivity of phosphorus bonds. Final purification, usually crystallisation or solvent washing, yields technical grade lythidathion for formulation. | [Mechanism of action]
Acetylcholinesterase (AchE) inhibitor. | [Pesticide Type]
Insecticide |
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