| Identification | Back Directory | [Name]
3-Pyridinecarboxamide, N-[4-(chlorodifluoromethoxy)phenyl]-5-(6-cyclopropyl-6,7-dihydro-5-oxo-5H-pyrrolo[3,4-b]pyridin-3-yl)-6-[(3R)-3-hydroxy-1-pyrrolidinyl]- | [CAS]
2669790-59-2 | [Synonyms]
BCR-ABL-IN-4
3-Pyridinecarboxamide, N-[4-(chlorodifluoromethoxy)phenyl]-5-(6-cyclopropyl-6,7-dihydro-5-oxo-5H-pyrrolo[3,4-b]pyridin-3-yl)-6-[(3R)-3-hydroxy-1-pyrrolidinyl]- | [Molecular Formula]
C27H24ClF2N5O4 | [MOL File]
2669790-59-2.mol | [Molecular Weight]
555.96 |
| Hazard Information | Back Directory | [Uses]
BCR-ABL-IN-4 is a BCR-ABL inhibitor with anticancer effects. BCR-ABL-IN-4 inhibits the cancer cell growth with IC50 values of 0.67 nM and 16 nM for K562 cells and BCR-ABL T315I transfected Ba/F3 cells, respectively (WO2021143927A1; compound 11)[1]. | [References]
[1] Yinsheng Zhang, et al. Compound acting as bcr-abl inhibitor. WO2021143927A1. |
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