| Chemical Properties | Back Directory | [Boiling point ]
668.3±55.0 °C(predicted) | [density ]
1.276±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
8.77±0.30(predicted) |
| Hazard Information | Back Directory | [Uses]
SelB-1 serves as a dual inhibitor for Topoisomerase I/II. SelB-1 possesses anticancer activity and can be utilized in the research of prostate cancer and colon cancer. Furthermore, SelB-1 is also capable of inducing autophagy gene expression and lipid peroxidation, while simultaneously reducing the level of GSH[1]. | [References]
[1] D?nmez S, et al. Selagibenzophenone B and Its Derivatives: SelB-1, a Dual Topoisomerase I/II Inhibitor Identified through In Vitro and In Silico Analyses. ACS Bio Med Chem Au. 2024 Jul 26;4(4):178-189. DOI:10.1021/acsbiomedchemau.4c00027 |
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