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2675-35-6

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2675-35-6 Structure

2675-35-6 Structure
IdentificationBack Directory
[Name]

Sivifene
[CAS]

2675-35-6
[Synonyms]

A007
A-007
A 007
sivifene
Unii-xav05295I5
Sivifene, 10 mM in DMSO
YOQPCWIXYUNEET-UHFFFAOYSA-N
4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone
Bis(4-hydroxyphenyl)methanone (2,4-dinitrophenyl)hydrazone
Methanone, bis(4-hydroxyphenyl)-, 2-(2,4-dinitrophenyl)hydrazone
[Molecular Formula]

C19H14N4O6
[MDL Number]

MFCD00339445
[MOL File]

2675-35-6.mol
[Molecular Weight]

394.34
Chemical PropertiesBack Directory
[density ]

1.47
[form ]

Solid
[color ]

Brown to reddish brown
Hazard InformationBack Directory
[Hazard]

Moderately toxic by ingestion.
[Uses]

Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors[1].
[References]

[1] Eilender D, et al. 4,4'-Dihydroxybenzophenone-2,4-dinitrophenylhydrazone (A-007): a topical treatment for cutaneous metastases from malignant cancers. Cancer Chemother Pharmacol. 2006 Jun;57(6):719-26. DOI:10.1007/s00280-005-0124-2
Safety DataBack Directory
[Toxicity]

LD50 oral in rat: 4300mg/kg
Spectrum DetailBack Directory
[Spectrum Detail]

Sivifene(2675-35-6)1HNMR
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