| Identification | Back Directory | [Name]
2-Piperazinecarboxamide, 4-[(4-aminophenyl)sulfonyl]-N-(2-furanylmethyl)-1-(3,4,5-trihydroxybenzoyl)- | [CAS]
2677762-43-3 | [Synonyms]
HIV-1 inhibitor-45
2-Piperazinecarboxamide, 4-[(4-aminophenyl)sulfonyl]-N-(2-furanylmethyl)-1-(3,4,5-trihydroxybenzoyl)- | [Molecular Formula]
C23H24N4O8S | [MOL File]
2677762-43-3.mol | [Molecular Weight]
516.52 |
| Hazard Information | Back Directory | [Uses]
HIV-1 inhibitor-45 (compound IA-6) is a potent HIV-1 RNase H inhibitor with an IC50 value of 0.067 μM. HIV-1 inhibitor-45 shows an antiviral activity[1]. | [IC 50]
HIV-1 | [References]
[1] Zhang L, et, al. Design, synthesis, and biological evaluation of novel double-winged galloyl derivatives as HIV-1 RNase H inhibitors. Eur J Med Chem. 2022 Jun 26;240:114563. DOI:10.1016/j.ejmech.2022.114563 |
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