| Identification | Back Directory | [Name]
2,4(1H,3H)-Pyrimidinedione, 5-[5-[3-chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl]-6-oxo[1(6H),3'-bipyridin]-3-yl]-1-methyl- | [CAS]
2679814-93-6 | [Synonyms]
2,4(1H,3H)-Pyrimidinedione, 5-[5-[3-chloro-5-[(2-chlorophenyl)methoxy]-4-fluorophenyl]-6-oxo[1(6H),3'-bipyridin]-3-yl]-1-methyl- | [Molecular Formula]
C28H19Cl2FN4O4 | [MOL File]
2679814-93-6.mol | [Molecular Weight]
565.38 |
| Hazard Information | Back Directory | [Description]
Mpro 61 is a potent non-covalent inhibitor of SARS-CoV-2 main protease. | [Uses]
SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19[1]. | [storage]
Store at -20°C | [References]
[1] Zhang CH, et al. Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 2021 Jul 14;12(8):1325-1332. DOI:10.1021/acsmedchemlett.1c00326 |
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