| Identification | Back Directory | [Name]
CFM1571hydrochloride | [CAS]
268725-86-6 | [Synonyms]
CFM 1571
CFM1571hydrochloride
1H-Pyrazole-5-carboxamide, 3-[3-(dimethylamino)propoxy]-N-(4-methoxyphenyl)-1-(phenylmethyl)-
3-[3-(Dimethylamino)propoxy]-N-(4-methoxyphenyl)-1-(phenylmethyl)-1H-pyrazole-5-carboxamidehydrochloride | [Molecular Formula]
C23H28N4O3 | [MDL Number]
MFCD09753275 | [MOL File]
268725-86-6.mol | [Molecular Weight]
408.49 |
| Chemical Properties | Back Directory | [Melting point ]
>182° C (dec.) | [storage temp. ]
Store at +4°C | [solubility ]
DMSO (Slghtly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
CFM 1571 is the free base of CFM 1571 Hydrochloride (C291720), which acts as a soluble guanylyl cyclase (sGC) activator while ignoring adenylyl cyclase. Inhibits collagen-stimulated platelet aggregation in vitro. | [Definition]
ChEBI: 5-[3-(dimethylamino)propoxy]-N-(4-methoxyphenyl)-2-(phenylmethyl)-3-pyrazolecarboxamide is an aromatic amide. | [Biological Activity]
Soluble guanylyl cyclase (sGC) activator (EC 50 = 5.49 μ M). Does not activate adenylyl cyclase, shows no significant inhibition of phosphodiesterases and displays minimal inhibition of iNOS (25%) and nNOS (17%). Inhibits collagen-stimulated platelet aggregation in vitro (IC 50 = 2.84 μ M). |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|