| Hazard Information | Back Directory | [Uses]
PROTAC SMARCA2/4 degrader-37 (Example 4) is a PROTAC-based SMARCA2/4 degrader, with an IC50 of ≤0.1 μM (Pink: SMARCA2/4 lignad (HY-172446); Black: CRBN ligand (HY-41547); Linker (HY-N2407))[1]. | [References]
[1] Preparation of bifunctional PROTAC compounds, compositions, and methods for degradation of targeted SMARCA2, SMARCA4 or BRM proteins. Patent WO2021163302 A1. |
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