| Identification | Back Directory | [Name]
3-Quinolinecarboxamide, 1-cyclopropyl-N-[5-[[(3,4-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- | [CAS]
2691895-64-2 | [Synonyms]
Anticancer agent 66
3-Quinolinecarboxamide, 1-cyclopropyl-N-[5-[[(3,4-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- | [Molecular Formula]
C26H23Cl2FN6O2S2 | [MOL File]
2691895-64-2.mol | [Molecular Weight]
605.53 |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 66 (Compound 13e) is an anti-cancer agent. Anticancer agent 66 induces apoptosis and increases sub-G1 cell population in MCF-7 cells. Anticancer agent 66 is a ciprofloxacin analog[1]. | [References]
[1] Ahadi H, et al. Synthesis and biological assessment of ciprofloxacin-derived 1,3,4-thiadiazoles as anticancer agents. Bioorg Chem. 2020;105:104383. DOI:10.1016/j.bioorg.2020.104383 |
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