| Identification | Back Directory | [Name]
Benzenamine, 4-methoxy-N-[4-(2-methyl-4-thiazolyl)phenyl]- | [CAS]
2692652-49-4 | [Synonyms]
FabH-IN-1
Benzenamine, 4-methoxy-N-[4-(2-methyl-4-thiazolyl)phenyl]- | [Molecular Formula]
C17H16N2OS | [MOL File]
2692652-49-4.mol | [Molecular Weight]
296.39 |
| Hazard Information | Back Directory | [Uses]
FabH-IN-1 (compound 3f) is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target. FabH-IN-1 is effective against gram-positive and gram-negative. FabH-IN-1 is also a good antioxidant[1]. | [References]
[1] Ahmad H, et, al. A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors. Bioorg Chem. 2020 Dec;105:104426. DOI:10.1016/j.bioorg.2020.104426 |
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