| Identification | Back Directory | [Name]
POLY-L-ARGININE HYDROCHLORIDE | [CAS]
26982-20-7 | [Synonyms]
mw10000-20000
POLY-L-ARGININE HCL
Arg dihydrochloride
Poly-L-Arg HCl MW=29KDa
Poly-L-Arg HCl MW=1.9KDa
Poly-L-Arg HCl MW=9.6KDa
Poly-L-Arg HCl MW=5.8KDa
Poly-L-Arg HCl MW=38.5KDa
POLY-L-ARGININE HYDROCHLORIDE
POLY-L-ARGININE HCL MOL WT 15000-700
POLY-L-ARGININE HYDROCHLORIDE MOL. W
L-ARGININE, HOMOPOLYMER, HYDROCHLORIDE
POLY-L-ARGININE HCL MOL WT 15000-70000
poly-L-arginine hcl mol wt 70000-150000
POLY-L-ARGININE HYDROCHLORIDE USP/EP/BP
Poly-L-arginine hydrochloride mol wt >70,000
poly-L-arginine hydrochloride mol. wt.*5000-15000
Poly-L-arginine hydrochloride, mol wt 15,000-70,000 | [Molecular Formula]
C6H14N4O2 | [MDL Number]
MFCD00166393 | [MOL File]
26982-20-7.mol | [Molecular Weight]
174.2 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [form ]
powder or solid | [color ]
white to off-white | [Cosmetics Ingredients Functions]
NAIL CONDITIONING | [InChI]
InChI=1/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/s3 | [InChIKey]
ODKSFYDXXFIFQN-UFLUHPNLNA-N | [SMILES]
C([C@H](N)C(=O)O)CCNC(N)=N |&1:1,r| |
| Hazard Information | Back Directory | [Uses]
Poly-L-arginine hydrochloride has been used:
- as polyelectrolyte solution in the synthesis of biodegradable capsules
- as layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shells
- in assay for the determination of binding activity of C-reactive protein for polycationic ligands
| [Uses]
Poly-L-arginine hydrochloride has been used:
- to generate complex with stimulatory RNA isRNA9.2 as in neutrophils
- used in ribosomal RNA transfection into human monocytic THP-1 cells
- for coating alginate capsule beads
| [General Description]
Poly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality. | [Biochem/physiol Actions]
Poly-L-arginine (PLA) possesses anti-bacterial activity. It has a greater capacity to enhance membrane permeability. PLA at lower concentration enhances cell proliferation and at higher concentration acts as antiproliferative agent. |
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