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2701565-75-3

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2701565-75-3 Structure

2701565-75-3 Structure
IdentificationBack Directory
[Name]

E3 ligase Ligand 13
[CAS]

2701565-75-3
[Synonyms]

E3 ligase Ligand 13
Hazard InformationBack Directory
[Uses]

E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[IC 50]

IAP
[References]

[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168
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