| Identification | Back Directory | [Name]
1H-Benz[e]indolium, 2-[2-[3-[2-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl-, tetrafluoroborate(1-) (1:1) | [CAS]
2708152-94-5 | [Synonyms]
1H-Benz[e]indolium, 2-[2-[3-[2-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl-, tetrafluoroborate(1-) (1:1) | [Molecular Formula]
C49H52BF4N3O4 | [MOL File]
2708152-94-5.mol | [Molecular Weight]
833.78 |
| Chemical Properties | Back Directory | [solubility ]
soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water | [form ]
Solid | [color ]
Brown to black | [Appearance]
green powder |
| Hazard Information | Back Directory | [Description]
Cyanine7.5 is a NIR dye with very long-wave emission. This product is amine-reactive derivative of this fluorophore.
Near infrared radiation readily penetrates tissues and can be used for imaging applications in vivo.
This product can be used for the labeling of various biomolecules containing amine groups, such as proteins and peptides, to track their distribution in organism in vivo by NIR imaging.
Increased rigidity of central polymethyne moiety allows to increase quantum yield by 20% compared to parent structure of Cy7.5® NHS. | [Uses]
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study[1]. | [References]
[1] Qi T, et al. A pH-Activatable nanoparticle for dual-stage precisely mitochondria-targeted photodynamic anticancer therapy. Biomaterials. 2019 Aug;213:119219. DOI:10.1016/j.biomaterials.2019.05.030 | [Abs/Em Maxima]
788/808 nm | [Fluoresene quantum yield]
0.1 | [Extinction Coefficient]
223000 |
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