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27098-24-4

27098-24-4 Structure

27098-24-4 Structure
IdentificationBack Directory
[Name]

1-stearoyl-2-linoleoylphosphatidylcholine
[CAS]

27098-24-4
[Synonyms]

SLPC
Stearoyl-linoleoyl phosphatidylcholine
1-stearoyl-2-linoleoylphosphatidylcholine
1-stearoyl-2-linoleyl-sn-glycero-3-phosphoryl-choline
1-STEAROYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;18:0-18:2 PC
[O-(1-O-Stearoyl-2-O-linoleoyl-L-glycero-3-phospho)choline]anion
[O-[1-O-Octadecanoyl-2-O-[(9Z,12Z)-1-oxo-9,12-octadecadienyl]-L-glycero-3-phospho]choline]anion
(R)-2-(((9Z,12Z)-octadeca-9,12-dienoyl)oxy)-3-(stearoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
[Molecular Formula]

C44H84NO8P
[MDL Number]

MFCD00674330
[MOL File]

27098-24-4.mol
[Molecular Weight]

786.121
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

Solid
[color ]

White to off-white
[InChIKey]

FORFDCPQKJHEBF-VPUSDGANSA-N
[SMILES]

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
Safety DataBack Directory
[Symbol(GHS) ]

Skull and Crossbones (GHS06)Health Hazard (GHS08)
GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H319-H331-H336-H351-H361d-H372
[Precautionary statements ]

P202-P301+P312-P302+P352-P304+P340+P311-P305+P351+P338-P308+P313
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

18:0-18:2 PC is suitable for use:
  • in the preparation of large unilamellar vesicles
  • in the preparation of liposomes
  • to prepare oxidised phospholipid by 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) for multiple reaction monitoring (MRM) analysis

[Uses]

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine s used in the preparation of a fiber with resistance to respiratory viral disease. The fiber has exogenous pulmonary surfactant which can enter the body through breathing and play an antiviral role.
[Definition]

ChEBI: 1-octadecanoyl-2-[(9Z,12Z)-octadecadienoyl]-sn-glycero-3-phosphocholine is a phosphatidylcholine 36:2 in which the acyl groups positions 1 and 2 are specified as octadecanoyl and (9Z,12Z)-octadecadienoyl respectively. It has a role as a mouse metabolite. It is functionally related to a linoleic acid and an octadecanoic acid.
[General Description]

18:0-18:2 PC is a non-fragmented oxidized phosphotidylcholine. It is a component of low density lipoprotein (LDL), which is a polyunsaturated fatty acid.
[Biochem/physiol Actions]

Phosphatidylcholine is one of the major glycerophospholipids of the eukaryotic membranes. It is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol.
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