| Identification | Back Directory | [Name]
Ethanone, 1-(2,2-dimethyl-1,3-benzodioxol-5-yl)-2-(1H-imidazol-1-yl)-, O-(2-naphthalenylcarbonyl)oxime, (1E)- | [CAS]
2713548-95-7 | [Synonyms]
AChE-IN-3
Ethanone, 1-(2,2-dimethyl-1,3-benzodioxol-5-yl)-2-(1H-imidazol-1-yl)-, O-(2-naphthalenylcarbonyl)oxime, (1E)- | [Molecular Formula]
C25H21N3O4 | [MOL File]
2713548-95-7.mol | [Molecular Weight]
427.45 |
| Chemical Properties | Back Directory | [Boiling point ]
622.3±65.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (233.95 mM; Need ultrasonic) | [form ]
Solid | [pka]
5.79±0.12(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
AChE-IN-3 shows moderate inhibitory activity against AChE and strong NO inhibitory activity with an EC50 of 0.57 μM. | [Biological Activity]
AChE-IN-3 shows moderate inhibitory activity against AChE and strong NO inhibitory activity with an EC50 of 0.57 μM. | [References]
[1]. Ren B, et al. Imidazolylacetophenone oxime-based multifunctional neuroprotective agents: Discovery and structure-activity relationships. Eur J Med Chem. 2022 Jan 15;228:114031. |
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| Company Name: |
Bide Pharmatech Ltd.
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| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
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