| Hazard Information | Back Directory | [Uses]
SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)[1]. | [References]
[1] Xin Li, et al. Pyrimidobicyclic derivatives, their preparation method and their application in medicine. Patent WO2021203768A1. |
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