| Identification | Back Directory | [Name]
8-Br-cGMP-AM | [CAS]
272445-71-3 | [Synonyms]
8-Br-cGMP-AM
Guanosine, 8-bromo-, cyclic 3',5'-[(acetyloxy)methyl phosphate] (9CI) | [Molecular Formula]
C13H15BrN5O9P | [MOL File]
272445-71-3.mol | [Molecular Weight]
496.17 |
| Hazard Information | Back Directory | [Uses]
8-Br-cGMP-AM is a derivative of 8-Br-cGMP. As an activator of PKG (cGMP-dependent protein kinase), it can lead to a variety of biological effects such as vasodilation and platelet inhibition. 8-Br-cGMP-AM can be used in the study of cardiovascular diseases[1]. | [References]
[1] Butt E. cGMP-dependent protein kinase modulators[J]. cGMP: Generators, Effectors and Therapeutic Implications, 2009: 409-421. DOI:10.1007/978-3-540-68964-5_17 |
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