| Identification | Back Directory | [Name]
8-pCPT-cGMP-AM | [CAS]
272445-72-4 | [Synonyms]
8-pCPT-cGMP-AM
Guanosine, 8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[(acetyloxy)methyl phosphate] (9CI) | [Molecular Formula]
C19H19ClN5O9PS | [MOL File]
272445-72-4.mol | [Molecular Weight]
559.87 |
| Hazard Information | Back Directory | [Uses]
8-pCPT-cGMP-AM (8-(4-Chlorophenylthio)-cGMP-AM) is a highly membrane permeable prodrug of the PKG agonist 8-pCPT-cGMP, which increases the membrane permeability of cGMP and is converted to its active form by esterase hydrolysis within the cell, thereby activating PKG. 8-pCPT-cGMP-AM can be used to explore the role of cGMP signaling in neural plasticity and memory formation[1]. | [References]
[1] Butt E. cGMP-dependent protein kinase modulators[J]. cGMP: Generators, Effectors and Therapeutic Implications, 2009: 409-421. DOI:10.1007/978-3-540-68964-5_17 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList1701258/0_EN.htm |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|