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2727083-99-8

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2727083-99-8 Structure

2727083-99-8 Structure
IdentificationBack Directory
[Name]

CXF-007
[CAS]

2727083-99-8
[Synonyms]

CXF-007
[Molecular Formula]

C34H33N7O5
[MOL File]

2727083-99-8.mol
[Molecular Weight]

619.67
Chemical PropertiesBack Directory
[density ]

1.326±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

13.16±0.70(predicted)
Hazard InformationBack Directory
[Uses]

CXF-007 is a potent and specific FGFR4 inhibitor with a IC50 value of 7 nM. CXF-007 has antitumor activity[1].
[IC 50]

FGFR4: 7 nM (IC50)
[References]

[1] Chen X, et al. Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4. Eur J Med Chem. 2024 Feb 28;268:116281. DOI:10.1016/j.ejmech.2024.116281
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