| Identification | Back Directory | [Name]
Methanone, [3-(dimethylamino)-1-azetidinyl][4-[2-(1,2,3,4,4a,5-hexahydro-3-methylpyrazino[2,1-c][1,4]benzoxazin-8-yl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]phenyl]- | [CAS]
2734168-78-4 | [Synonyms]
HPK1-IN-9
Methanone, [3-(dimethylamino)-1-azetidinyl][4-[2-(1,2,3,4,4a,5-hexahydro-3-methylpyrazino[2,1-c][1,4]benzoxazin-8-yl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]phenyl]- | [Molecular Formula]
C30H33N7O2 | [MOL File]
2734168-78-4.mol | [Molecular Weight]
523.63 |
| Hazard Information | Back Directory | [Uses]
HPK1-IN-9 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-9 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 112) [1]. | [References]
[1] Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1. |
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