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2734858-36-5

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2734858-36-5 Structure

2734858-36-5 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2734858-36-5
[Synonyms]

[Molecular Formula]

C20H25N10NaO13P2
[MOL File]

2734858-36-5.mol
[Molecular Weight]

698.41
Chemical PropertiesBack Directory
[solubility ]

Water: Soluble
[form ]

Solid
[color ]

White to off-white
[Water Solubility ]

Soluble to 50 mM in water
Hazard InformationBack Directory
[Uses]

2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm[1].
[storage]

Store at -20°C
[References]

[1] Zhang X, et al. Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING. Mol Cell. 2013 Jul 25;51(2):226-35. DOI:10.1016/j.molcel.2013.05.022
Spectrum DetailBack Directory
[Spectrum Detail]

2'-3'-cyclic GMP-AMP sodium(2734858-36-5)1HNMR
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