| Chemical Properties | Back Directory | [Boiling point ]
602.581±55.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.148±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
14.138±0.46(predicted) |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2-IN-75 (compound 13) is a SARS-CoV-2 inhibitor based on chloroacetamide inhibition. SARS-CoV-2-IN-75 inhibits cellular SARS-CoV-2 replication with an EC68 (half-log reduction in viral titer) of 3 μM[1]. | [References]
[1] Ashraf-Uz-Zaman M, et al. Design, Synthesis, X-ray Crystallography, and Biological Activities of Covalent, Non-Peptidic Inhibitors of SARS-CoV-2 Main Protease. ACS Infect Dis. 2024 Jan 8. DOI:10.1021/acsinfecdis.3c00565 |
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