| Identification | Back Directory | [Name]
Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]- | [CAS]
2738526-22-0 | [Synonyms]
Neuraminidase-IN-6
Acetamide, N-(4-ethylphenyl)-2-[[3-(2-furanyl)-1H-1,2,4-triazol-5-yl]thio]- | [Molecular Formula]
C16H16N4O2S | [MOL File]
2738526-22-0.mol | [Molecular Weight]
328.39 |
| Hazard Information | Back Directory | [Uses]
Neuraminidase-IN-6 (Compound 5c) is a potent inhibitor of neuraminidase with an IC50 of 0.11 μM. Neuraminidase-IN-6 is a 1,3,4-triazole-3-acetamide derivative. Neuraminidase (NA) is an ideal target for the development of anti-influenza agents[1]. | [References]
[1] Shi L, et al. Design, synthesis and biological evaluation of 1,3,4-triazole-3-acetamide derivatives as potent neuraminidase inhibitors. Bioorg Med Chem Lett. 2022;61:128590. DOI:10.1016/j.bmcl.2022.128590 |
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