| Identification | Back Directory | [Name]
Acetamide, N-[4-[[2-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-1-pyrrolidinyl]carbonyl]-3-methoxyphenyl]- | [CAS]
2743432-81-5 | [Synonyms]
POP-IN-2
Acetamide, N-[4-[[2-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-1-pyrrolidinyl]carbonyl]-3-methoxyphenyl]- | [Molecular Formula]
C24H33BN2O5 | [MOL File]
2743432-81-5.mol | [Molecular Weight]
440.34 |
| Hazard Information | Back Directory | [Uses]
POP-IN-2 (Compound 7k) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 6 nM. POP-IN-2 can be used for studying neurodegenerative diseases and cancer[1]. | [References]
[1] Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783. DOI:10.1016/j.ejmech.2019.111783 |
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