| Identification | Back Directory | [Name]
3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- | [CAS]
2749554-48-9 | [Synonyms]
OXPHOS-IN-1
3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- | [Molecular Formula]
C19H29N3O6S2 | [MOL File]
2749554-48-9.mol | [Molecular Weight]
459.58 |
| Hazard Information | Back Directory | [Uses]
OXPHOS-IN-1 (compound 2) is a oxidative phosphorylation (OXPHOS) inhibitor. OXPHOS-IN-1 inhibits the cells growth of MIA PaCa-2 and BxPC-3 cells with IC50s of 2.34 μM and 13.82 μM, respectively[1]. | [References]
[1] Ding Xue, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022 Feb 24;65(4):3404-3419. DOI:10.1021/acs.jmedchem.1c01934 |
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