| Identification | Back Directory | [Name]
Cyclohexanol, 4-[4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-8,9-dihydro-2-methylfuro[2,3-h]quinazolin-6-yl]-, trans- | [CAS]
2751718-88-2 | [Synonyms]
SOS1-IN-6
Cyclohexanol, 4-[4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-8,9-dihydro-2-methylfuro[2,3-h]quinazolin-6-yl]-, trans- | [Molecular Formula]
C26H28F3N3O2 | [MOL File]
2751718-88-2.mol | [Molecular Weight]
471.51 |
| Hazard Information | Back Directory | [Uses]
SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC50s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively[1]. | [IC 50]
SOS1-G12D: 14.9 nM (IC50); SOS1-G12V: 73.3 nM (IC50) | [References]
[1] Fused quinazoline derivative, preparation method therefor and application thereof in medicine. WO2021249475A1. |
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