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2755180-37-9

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2755180-37-9 Structure

2755180-37-9 Structure

Identification	Back Directory
[Name] BT424
[CAS] 2755180-37-9
[Synonyms] BT424
[Molecular Formula] C22H15BCl2N2O2
[MOL File] 2755180-37-9.mol
[Molecular Weight] 421.08

Chemical Properties	Back Directory
[Boiling point ] 547.6±60.0 °C(predicted)
[density ] 1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] -9.28±0.20(predicted)
[color ] White to off-white

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[Uses] BT424 is a specific HCK inhibitor. BT424 can regulate macrophage activation and autophagy in vitro. BT424 ameliorates inflammation and kidney fibrosis in UUO model[1].
[References] [1] Chen M, et al. HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy. Nat Commun. 2023 Jul 18;14(1):4297. DOI:10.1038/s41467-023-40086-3

2755180-37-9 suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+17819995354 , +17819995354
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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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