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2755415-30-4

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2755415-30-4 Structure

2755415-30-4 Structure
IdentificationBack Directory
[Name]

Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-
[CAS]

2755415-30-4
[Synonyms]

SOS1-IN-7
Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-6-(cis-1,4-dihydroxycyclohexyl)-2-methyl-
[Molecular Formula]

C23H25F3N4O3
[MOL File]

2755415-30-4.mol
[Molecular Weight]

462.46
Chemical PropertiesBack Directory
[Boiling point ]

609.0±65.0 °C(Predicted)
[density ]

1.48±0.1 g/cm3(Predicted)
[pka]

12.55±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively[1].
[IC 50]

SOS1-G12D: 20 nM (IC50); SOS1-G12V: 67 nM (IC50)
[References]

[1] Pyridine-pyrimidine derivative, preparation method therefor and pharmaceutical use thereof. WO2021249519A1.
2755415-30-4 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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