| Identification | Back Directory | [Name]
1-Propanone, 1-[(2R)-3,4-dihydro-7-methyl-6-(2-pyrimidinyl)spiro[1,8-naphthyridine-2(1H),3′-pyrrolidin]-1′-yl]-2-(5-fluoro-2-methoxy-4-pyridinyl)-, (2R)- | [CAS]
2755890-68-5 | [Synonyms]
1-Propanone, 1-[(2R)-3,4-dihydro-7-methyl-6-(2-pyrimidinyl)spiro[1,8-naphthyridine-2(1H),3′-pyrrolidin]-1′-yl]-2-(5-fluoro-2-methoxy-4-pyridinyl)-, (2R)- | [Molecular Formula]
C25H27FN6O2 | [MOL File]
2755890-68-5.mol | [Molecular Weight]
462.52 |
| Chemical Properties | Back Directory | [Boiling point ]
627.3±55.0 °C(predicted) | [density ]
1.34±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
5.15±0.20(predicted) |
| Hazard Information | Back Directory | [Uses]
(2R,2R)-PF-07258669 is a MC4R (melanocortin 4 receptor) antagonist. (2R,2R)-PF-07258669 can be used in the study of regulating appetite and energy expenditure[1]. | [References]
[1] Cao Q, et al. Modular, automated synthesis of spirocyclic tetrahydronaphthyridines from primary alkylamines[J]. Communications Chemistry, 2023, 6(1): 215. DOI:10.1038/s42004-023-01012-2 |
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