| Identification | Back Directory | [Name]
2(1H)-Quinolinone, 1-(2-chlorophenyl)-4-(methylamino)-7-(trifluoromethyl)- | [CAS]
2756458-55-4 | [Synonyms]
MAT2A-IN-5
2(1H)-Quinolinone, 1-(2-chlorophenyl)-4-(methylamino)-7-(trifluoromethyl)- | [Molecular Formula]
C17H12ClF3N2O | [MOL File]
2756458-55-4.mol | [Molecular Weight]
352.74 |
| Hazard Information | Back Directory | [Uses]
MAT2A-IN-5 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-5 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-5 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 1)[1]. | [References]
[1] Li Zhen, et al. Bicyclic compounds. Patent WO2021254529A1. |
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