| Chemical Properties | Back Directory | [Boiling point ]
574.1±50.0 °C(Predicted) | [density ]
1.293±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 62.5 mg/mL (201.39 mM; Need ultrasonic) | [form ]
Solid | [pka]
12.31±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
SB-216 is a potent tubulin polymerization inhibitor. SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer.? SB-216 can be used for cancer research[1]. | [storage]
Store at -20°C | [References]
[1] Souvik Banerjee, et al. X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor. J Med Chem. 2021 Sep 9;64(17):13072-13095. DOI:10.1021/acs.jmedchem.1c01202 |
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