| Identification | Back Directory | [Name]
Betulin-3-acetate | [CAS]
27570-20-3 | [Synonyms]
3-Acetyl Betulin
Betulin-3-acetate
Betulin monoacetate
3β-Acetoxylupa-20(29)-ene-28-ol
Lup-20(29)-ene-3β,28-diol 3-acetate
Lupane-20(29)-ene-3β,28-diol 3-acetate
Betulin 3-O-acetate, 97%, Semi-Synthetic
Lup-20(29)-ene-3,28-diol, 3-acetate, (3β)- | [Molecular Formula]
C32H52O3 | [MOL File]
27570-20-3.mol | [Molecular Weight]
484.75 |
| Hazard Information | Back Directory | [Uses]
3-O-Acetylbetulin is a derivative of Betulin (HY-N0083), a sterol regulatory element-binding protein (SREBP) inhibitor. 3-O-Acetylbetulin can be utilized in synthesis of other betulin derivatives[1]. | [Biological Activity]
3-Acetyl betulin is a pentacyclic triterpenoid and derivative of the cholesterol biosynthesis inhibitor betulin .1,2 It is an intermediate in the synthesis of various lupane and germanicane triterpenes and saponins with anticancer activity. | [storage]
-20°C | [References]
1.Thibeault, D., Gauthier, C., Legault, J., et al.Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3β-O-monodesmosidic saponins starting from betulinBioorg. Med. Chem.15(18)6144-6157(2007)
2.B?benek, E., Kadela-Tomanek, M., Chrobak, E., et al.Novel triazoles of 3-acetylbetulin and betulone as anticancer agentsMed. Chem. Res.27(9)2051-2061(2018)
|
|
| Company Name: |
ChemeGen
|
| Tel: |
18818260767 |
| Website: |
https://www.chemegen.com |
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
|