| Identification | Back Directory | [Name]
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(2-benzothiazolylthio)methyl]-7-methoxy-8-oxo-, (6R,7S)- | [CAS]
2757462-75-0 | [Synonyms]
trans-Cephalosporin
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(2-benzothiazolylthio)methyl]-7-methoxy-8-oxo-, (6R,7S)- | [Molecular Formula]
C16H14N2O4S3 | [MOL File]
2757462-75-0.mol | [Molecular Weight]
394.49 |
| Hazard Information | Back Directory | [Uses]
Trans substituted cephalosporin is an effective NDM-1 inhibitor，with an IC50 value of 0.13 μM. | [IC 50]
NDM-1: 0.13 μM (IC50) | [References]
[1] Hu L,et al. Stereochemically altered cephalosporins as potent inhibitors of New Delhi metallo-β-lactamases. Eur J Med Chem. 2022 Feb 4;232:114174. DOI:10.1016/j.ejmech.2022.114174 |
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