| Identification | Back Directory | [Name]
2(1H)-Quinazolinone, 6-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1-methyl-4-phenyl-3-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]- | [CAS]
2757865-63-5 | [Synonyms]
BRD4 Inhibitor-19
2(1H)-Quinazolinone, 6-(3,5-dimethyl-4-isoxazolyl)-3,4-dihydro-1-methyl-4-phenyl-3-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]- | [Molecular Formula]
C29H25N5O3 | [MOL File]
2757865-63-5.mol | [Molecular Weight]
491.54 |
| Hazard Information | Back Directory | [Uses]
BRD4 Inhibitor-19 is a?BET?inhibitor with an?IC50?of 55 nM for BRD4-BD1. BRD4 Inhibitor-19 can be used for multiple myeloma research[1]. | [IC 50]
BD1: 55 nM (IC50) | [References]
[1] Lincheng Fang, et al. Discovery of 3,5-dimethylisoxazole derivatives as novel, potent inhibitors for bromodomain and extraterminal domain (BET) family. Bioorg Med Chem. 2021 Jun 1;39:116133. DOI:10.1016/j.bmc.2021.116133 |
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