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2758337-19-6

2758337-19-6 Structure

2758337-19-6 Structure
IdentificationBack Directory
[Name]

6-(4-Aminobutoxy)-N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide
[CAS]

2758337-19-6
[Synonyms]

UAMC1110-NH2
6-(4-Aminobutoxy)-N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide
[Molecular Formula]

C21H23F2N5O3
[MOL File]

2758337-19-6.mol
[Molecular Weight]

431.44
Chemical PropertiesBack Directory
[Boiling point ]

752.0±60.0 °C(Predicted)
[density ]

1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka]

12.05±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

NH2-UAMC1110 is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1].
[References]

[1] Euy Sung Moon, et al. Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators. EJNMMI Radiopharm Chem. 2020 Jul 29;5(1):19. DOI:10.1186/s41181-020-00102-z
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