| Identification | Back Directory | [Name]
2H-Pyran-2-methanol, 5-[8-amino-1-[4-(difluorophenylmethyl)phenyl]imidazo[1,5-a]pyrazin-3-yl]tetrahydro- | [CAS]
2758596-07-3 | [Synonyms]
BTK-IN-10
2H-Pyran-2-methanol, 5-[8-amino-1-[4-(difluorophenylmethyl)phenyl]imidazo[1,5-a]pyrazin-3-yl]tetrahydro- | [Molecular Formula]
C25H24F2N4O2 | [MOL File]
2758596-07-3.mol | [Molecular Weight]
450.48 |
| Hazard Information | Back Directory | [Uses]
BTK-IN-10 is a potent BTK inhibitor with IC50s of <5 nM for wild-type BTK or mutated BTK (C481S), respectively (WO2022012509A1; example 111)[1]. | [References]
[1] Chunchao Yue, et al. Compound as brain-permeable btk or her2 inhibitor, preparation method therefor, and use thereof. WO2022012509A1. |
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