| Identification | Back Directory | [Name]
2-Thiophenecarboxamide, 3-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]- | [CAS]
2758802-02-5 | [Synonyms]
3-(3-Chloro-4-hydroxybenzamido)-N-(2-methoxyphenethyl)thiophene-2-carboxamide
2-Thiophenecarboxamide, 3-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]- | [Molecular Formula]
C21H19ClN2O4S | [MOL File]
2758802-02-5.mol | [Molecular Weight]
430.9 |
| Chemical Properties | Back Directory | [Boiling point ]
593.6±50.0 °C(Predicted) | [density ]
1.391±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
6.87±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
HSD17B13-IN-8 (1) is a 17β-Hydroxysteroid dehydrogenases (HSD17B13) inhibitor, with IC50 values of <0.1 μM for Estradiol and <1 μM for LTB3. Used in NAFLD (Nonalcoholic fatty liver diseases) research[1]. | [References]
[1] Joshua Odingo, et al. Thiophene hsd17b13 inhibitors and uses thereof. Patent WO2022020714. |
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