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2759037-58-4

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2759037-58-4 Structure

2759037-58-4 Structure
IdentificationBack Directory
[Name]

BI-10
[CAS]

2759037-58-4
[Synonyms]

BI-10
Phenol, 2-bromo-6-(di-1H-indol-3-ylmethyl)-
[Molecular Formula]

C23H17BrN2O
[MOL File]

2759037-58-4.mol
[Molecular Weight]

417.3
Chemical PropertiesBack Directory
[Boiling point ]

618.1±50.0 °C(Predicted)
[density ]

1.533±0.06 g/cm3(Predicted)
[pka]

8.59±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

BI-10 is an antifungal compound. BI-10 combined with Fluconazole can inhibit hyphal growth, result in ROS accumulation, and decrease mitochondrial membrane potential (MMP) as well as altering membrane permeability[1].
[References]

[1] Jiang Y, et al. Synthesis and antifungal evaluation of phenol-derived bis(indolyl)methanes combined with FLC against Candida albicans. Bioorg Med Chem Lett. 2022;58:128525. DOI:10.1016/j.bmcl.2022.128525
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