| Identification | Back Directory | [Name]
2-Piperazineacetonitrile, 4-[2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-7-(1-naphthalenylmethyl)imidazo[2,1-f][1,2,4]triazin-4-yl]-1-(1-oxo-2-propen-1-yl)-, (2S)- | [CAS]
2760354-12-7 | [Synonyms]
KRAS G12C inhibitor 50
2-Piperazineacetonitrile, 4-[2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-7-(1-naphthalenylmethyl)imidazo[2,1-f][1,2,4]triazin-4-yl]-1-(1-oxo-2-propen-1-yl)-, (2S)- | [Molecular Formula]
C31H34N8O2 | [MOL File]
2760354-12-7.mol | [Molecular Weight]
550.65 |
| Hazard Information | Back Directory | [Uses]
KRAS G12C inhibitor 50 (Example 4) is a KRAS G12C inhibitor with an IC50 of 46.7 nM[1]. | [IC 50]
KRAS(G12C): 46.7 nM (IC50) | [References]
[1] Guoliang Zhang, et al. Imidazotriazine and pyrrolopyrimidine derivatives as kras g12c inhibitors. WO2022028492A1. |
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