| Identification | Back Directory | [Name]
Urea, N-[[1-(4-chloro-3-fluorophenyl)-3-methyl-1H-1,2,4-triazol-5-yl]methyl]-N′-[[1-(7-quinolinyl)-1H-1,2,4-triazol-5-yl]methyl]- | [CAS]
2761226-35-9 | [Synonyms]
Urea, N-[[1-(4-chloro-3-fluorophenyl)-3-methyl-1H-1,2,4-triazol-5-yl]methyl]-N′-[[1-(7-quinolinyl)-1H-1,2,4-triazol-5-yl]methyl]- | [Molecular Formula]
C23H19ClFN9O | [MOL File]
2761226-35-9.mol | [Molecular Weight]
491.91 |
| Hazard Information | Back Directory | [Uses]
PKR activator 5 (Compound 18) is an activator for pyruvate kinase R (PKR) with an AC50 of 28 nM[1]. | [References]
[1] Yu C, et al., The search for pyruvate kinase-R activators; from a HTS screening hit via an impurity to the discovery of a lead series. Bioorg Med Chem Lett. 2024 Jun 29;110:129865. DOI:10.1016/j.bmcl.2024.129865 |
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