| Identification | Back Directory | [Name]
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate | [CAS]
2761458-86-8 | [Synonyms]
YK009
decyl 4-(1-hydroxy-12-octyl-9-oxo-3-aza-10-oxaicos-3-yl)butanoate
2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2-hydroxyethyl)amino]hexanoate | [Molecular Formula]
C40H79NO5 | [MOL File]
2761458-86-8.mol | [Molecular Weight]
654.06 |
| Chemical Properties | Back Directory | [Boiling point ]
687.4±45.0 °C(Predicted) | [density ]
0.933±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [solubility ]
Ethanol: 5 mg/ml | [pka]
14.75±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
YK-009 is an ionizable cationic lipid (pKa = 6.512) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs).1 Administration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant mRNA in YK-009-containing LNPs induces the production of IgG that binds to the SARS-CoV-2 receptor-binding domain (RBD) in mice, with a boost in IgG titers 10 days after a second dose.WARNING This product is not for human or veterinary use. | [References]
[1] JINRONG LONG. Novel Ionizable Lipid Nanoparticles for SARS-CoV-2 Omicron mRNA Delivery[J]. Advanced Healthcare Materials, 2023, 12 13. DOI: 10.1002/adhm.202202590 |
|
| Company Name: |
DC Chemicals
|
| Telephone: |
021-58447131 13564518121 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList927327/0_EN.htm |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
| Company Name: |
Abosyn
|
| Telephone: |
0512-69561983 13914027025 |
| Website: |
abosyn.cn/ |
|